Changes in optic parameters of collagen fiber status of general bile duct in the development of acute cholangitis as a complication of coledocholethiasis
The aim of the work was to improve the results of surgical treatment of patients with benign biliary pathology complicated by acute cholangitis on the basis of analysis of optical changes in general bile duct walls, investigating structural changes in collagen fibers of common bile duct walls by the parameters of birefringence step and phenol index. The results of diagnostics and surgical treatment of 22 patients with acute cholangitis were analyzed. The diagnosis was verified on the basis of clinical, instrumental methods, by biochemical blood tests as well as bacteriologic analysis of bile. The diagnostic and prognostic value of optical and polarization microscopy as an intraoperative method to evaluate the loss of contractile function of bile ducts was assessed in comparison with other diagnostic methods.