Dynamic content pro- and anti-inflammatory cytokines in serum blood in response to polytrauma in the experiment
The pathogenesis of systemic violations of the conditions of experimental trauma leading value growth has content proinflammatory cytokines of TNF-β and interleukin-1 β in blood serum. A characteristic feature of their dynamics is 2 times increasing - on 3 and 21 days. The content of serum interleukin-6 undergoes severe vibration disturbances with a significant decrease to 3 days, a significant increase on day 7 and normalization for 14-28 days. Vibrational dynamics to polytraumashows content interleukin-10 too, which increases noted on 7 and 21 days in response serum.