Structural modifications of the thymic (hassall's) corpuscles under the condition of experimental burn disease and it's treatment by the infusion of lactoprotein with Sorbitol

Abstract

Ultrastructural examination showed that thymus of rat under the condition of experimental burn disease contains numerous highly keratinized Hassall's corpuscles in various stages of development. Epithelioreticulocytes represent the "starting point" in thymic corpuscles formation and transformation. The fast genesis of thymic corpuscles and intercorpuscular "binding" by means of epithelioreticulocytes causes the particular polymorphism of these corpuscles during burn disease. Intravenosis infusion of lactoprotein with sorbitol has membranoplastic influence on the thymic structure. Application of lactoprotein with sorbitol also promoted to structural modifications of thymic corpuscles, associated with the formation of "membrane-like complex".