Comparative description of influence of kvertulin on healing of traumatic injuries of mandible of rats at dysfunction of hepatobiliary tract in experiment

Abstract

An experiment was conducted on 80 white rats-males of line of Vistar, by mass 240-270 g. In the process of study rats were divided into 4 groups: control group (with the injury of mandible); experimental group №1 (with the injury of mandible and crossing of bile duct); experimental group №2 (with the injury of mandible, that in the day of injuring of jaw and the next 2 weeks, were added to the meal the kvertulin in the dose of 200 mg on the kilogram of mass of rat); experimental group №3 (with the injury of mandible and crossed bile duct, that in the day of injuring of jaw and the next 2 weeks, were added to the meal the Kvertulin in the dose of 200 mg on the kilogram of mass of rat). The injury of mandible to all rats was inflicted by a perforation and formation of defect. Further observed the clinical signs of healing of area of perforated defect. At diseases of hepatobiliary tract at the halves of the experienced animals were registered complications, that in 3,3 times more than in healthy ones. At the use the kverulin amount of complications diminishes in 2,6 times. The clinical manifestations of healing of perforated defect of mandible of rats on a background the use of kverulin get better on 4,1±0,7 days.