Clinical effectiv of therapeutic regimens of progesterone in IVF programs in women with tuboperitoneal of infertility

Abstract

The article was discussed the efficacy of treatment dose of progesterone Luteina in the dose 400 gr a day intravaginal in patients with tuboperitoneal factor of infertility. In patients with tuboperitoneal infertility in IVF who received a progesterone in the day of the trigger of the ovulation was diagnosed the increase in pregnancy rate compared to patients who received a progesterone in the day of the puncture of follicles. In particular there has been an increase in the frequency of child bearing in the patients who received a progesterone in the day of the puncture of follicles. Evaluating the effectiveness of therapeutic regimens of progesterone prescription in IVF programs by examining pregnancy, analysis of its course and outcomes in women with tubal-peritoneal factor of infertility. A comparative analysis of pregnancy rate and the flow through the clinical, biochemical and instrumental methods of research in cycles of stimulation in women of reproductive age with tubo-peritoneal infertility depending of the start of progesterone injections. It is proved that in patients with injection of progesterone on the day of triggers of ovulation were no statistically significant differences in rates of pregnancy and implantation compared with patients whom progestogen administered on the day of follicular puncture. However, there was a statistically significant difference in the number of clinical pregnancy, and multiple pregnancy in a subgroup of women who started use progesterone in the term of triggers of ovulation. In the study of problem of treatment of tubo- peritoneal infertility genesis by exploring therapeutic regimens of progestogen prescription in stimulated IVF cycles were found that using of progesterone in the triggers day of ovulation contributes to a full invasion of trophoblast implantation and quality that defines a successful outcome of pregnancy.