Applicability of rats wound splintmodel to study healing process of artificially contaminated wounds

  • V. M. Kondratiuk
  • O. V. Pashkovska
  • T. O. Zaitseva
  • Yu. R. Dyachok
Keywords: contaminated wound, model, splint-wound

Abstract

The process of healing wounds one of the key issues of modern medicine, but with the increase in injuries in the practice of Ukrainian military doctors acquires relevance. There are a large numbers of models of wounds in animals. Skin splint-wound is an interesting and accessible model that accurately reflects wound healing process. The study identified the advantages and disadvantages of using rats splintwound to study the healing process of contaminated wounds. Were defined the key points that affect the results of the experiment, namely a sequence of manipulation with control group and groups which underwent contamination, splintcreation, daily observation and recording of the changes in the wounds. The recommendations on the planning of the experiment are given. To prevent loss of observation units one should plan for the appropriate number of animals, taking into consideration the possible failures that we have highlighted.

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Published
2017-10-27
How to Cite
Kondratiuk, V. M., Pashkovska, O. V., Zaitseva, T. O., & Dyachok, Y. R. (2017). Applicability of rats wound splintmodel to study healing process of artificially contaminated wounds. Reports of Morphology, 22(2), 392-394. Retrieved from https://morphology-journal.com/index.php/journal/article/view/309