Features of skinfold thickness in men with benign nevi

Keywords: benign nevi, skinfold thickness, men.


Nevi, although benign neoplasms of the skin, but have a certain tendency to malignancy, which is influenced by various external and internal human factors. Predicting the risk of benign nevi against this background is an important topic for experimental research. The aim of the study was to establish the features of the skinfold thickness (SFT) in men of the first adult age with benign nevi. SFT was determined according to the Bunak scheme for men (aged 22-35 years) with melanocyte benign simple nevi (n=34), melanocyte benign dysplastic nevi (n=27), melanocyte benign congenital nevi (n=14) and non-melanocyte benign (n=17). The control group – SFT of 82 practically healthy men of the same age group was selected from the data bank of the Research Center of National Pirogov Memorial Medical University, Vinnytsya. Statistical processing of the results was performed in the license package “Statistica 5.5” using non-parametric evaluation methods. It was found that in practically healthy men higher than in patients – SFT on the anterior and posterior surfaces of the shoulder and thigh (in all groups of patients); SFT on the forearm, at the lower angle of the scapula, chest and shin (only in patients with melanocyte benign dysplastic nevi). Also in healthy men are found lower than in patients – SFT on the side (in all groups of patients); SFT in the abdomen (in patients with melanocyte benign simple and non-melanocyte benign nevi). When comparing SFT between patients with benign nevi, in most cases, lower values of SFT found in patients with melanocyte benign dysplastic nevi. The obtained results indicate the initial manifestations of abdominal (android) type of fat deposition in the body in patients with benign nevi (most pronounced in patients with melanocyte benign simple nevi).


[1] Adaji, A., Gaba, P., Lohse, C. M., & Brewer, J. D. (2016). Incidence of atypical nevi in Olmsted County: an epidemiological study. Journal of Cutaneous Pathology, 43(7), 557-563. doi: 10.1111/cup.12709
[2] Belbasis, L., Stefanaki, I., Stratigos, A. J., & Evangelou, E. (2016). Non-genetic risk factors for cutaneous melanoma and keratinocyte skin cancers: an umbrella review of meta-analyses. Journal of Dermatological Science, 84(3), 330-339. doi: 10.1016/j.jdermsci.2016.09.003
[3] Buendía‐Eisman, A., Paláu‐Lázaro, M. C., Arias‐Santiago, S., Cabrera‐León, A., & Serrano‐Ortega, S. (2012). Prevalence of melanocytic nevi in 8‐to 10‐year‐old children in Southern Spain and analysis of associated factors. Journal of the European Academy of Dermatology and Venereology, 26(12), 1558-1564. doi: 10.1111/j.1468-3083.2011.04342.x
[4] Bunak, V. V. (1941). Антропометрия [Anthropometry]. М.: Наркомпрос РСФСР – М.: People’s Commissariat of the RSFSR.
[5] Buster, K. J., You, Z., Fouad, M., & Elmets, C. (2012). Skin cancer risk perceptions: a comparison across ethnicity, age, education, gender, and income. Journal of the American Academy of Dermatology, 66(5), 771-779. doi: 10.1016/j.jaad.2011.05.021
[6] Dobbins, M., Decorby, K., & Choi, B. C. K. (2013). The association between obesity and cancer risk: a meta-analysis of observational studies from 1985 to 2011. International Scholarly Research Notices, 2013, 680536. doi: 10.5402/2013/680536
[7] Donkor, C. M., Aryee-Boi, J., Osazuwa, I. R., Afflu, F. K., & Alexis, A. F. (2021). Nevi. In Atlas of Dermatological Conditions in Populations of African Ancestry (pp. 207-217). Springer, Cham.
[8] Dusingize, J. C., Olsen, C. M., An, J., Pandeya, N., Law, M. H., Thompson, B. S. ... Whiteman, D. C. (2020). Body mass index and height and risk of cutaneous melanoma: Mendelian randomization analyses. International Journal of Epidemiology, 49(4), 1236-1245. doi: 10.1093/ije/dyaa009
[9] Ekwueme, D. U., Guy Jr, G. P., Li, C., Rim, S. H., Parelkar, P., & Chen, S. C. (2011). The health burden and economic costs of cutaneous melanoma mortality by race/ethnicity – United States, 2000 to 2006. Journal of the American Academy of Dermatology, 65(5), S133-e1. doi: 10.1016/j.jaad.2011.04.036
[10] Ferreira, L., Jham, B., Assi, R., Readinger, A., & Kessler, H. P. (2015). Oral melanocytic nevi: a clinicopathologic study of 100 cases. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 120(3), 358-367. doi: 10.1016/j.oooo.2015.05.008
[11] Hunt, R. D., Orlow, S. J., & Schaffer, J. V. (2014). Genital melanocytic nevi in children: experience in a pediatric dermatology practice. Journal of the American Academy of Dermatology, 70(3), 429-434. doi: 10.1016/j.jaad.2013.10.022
[12] Kachare, S. D., Agle, S. C., Englert, Z. P., Zervos, E. E., Vohra, N. A., Wong, J. H., & Fitzgerald, T. L. (2013). Malignant blue nevus: clinicopathologically similar to melanoma. The American Surgeon, 79(7), 651-656. doi: 10.1177/000313481307900706
[13] Kyrgidis, A. (2017). Risk factors. In Cutaneous Melanoma (pp. 11-25). Academic Press. doi: 10.1016/B978-0-12-804000-3.00002-8
[14] Lee, K. R., Seo, M. H., Do Han, K., Jung, J., & Hwang, I. C. (2018). Waist circumference and risk of 23 site-specific cancers: a population-based cohort study of Korean adults. British Journal of Cancer, 119(8), 1018-1027. doi: 10.1038/s41416-018-0214-7
[15] Leonardi-Bee, J., Ellison, T., & Bath-Hextall, F. (2011). Lifestyle factors of smoking, BMI and alcohol consumption on the risk of Non-Melanoma Skin cancer in adults: Systematic review. JBI Evidence Synthesis, 9(32), 1-18. doi: 10.11124/jbisrir-2011-409
[16] Monteagudo, B., Labandeira, J., Acevedo, A., Ramirez-Santos, A., Cabanillas, M., Corrales, A. ... Toribio, J. (2011). Prevalence and clinical features of congenital melanocytic nevi in 1,000 Spanish newborns. Actas Dermo-Sifiliográficas (English Edition), 102(2), 114-120. doi: 10.1016/S1578-2190(11)70768-5
[17] Potekayev, N. N., Shuginina, Y. К., Kuzmina, Т. S., & Arutyunyan, L. S. (2011). Дерматоскопия в клинической практике. Руководство для врачей [Dermatoscopy in clinical practice. A guide for doctors]. М: МДВ, 144 – М: МDV, 144.
[18] Sadoghi, B., Schmid-Zalaudek, K., Zalaudek, I., Fink-Puches, R., Niederkorn, A., Wolf, I. ... Richtig, E. (2021). Prevalence of nevi, atypical nevi, and lentigines in relation to tobacco smoking. Plos One, 16(7), e0254772. doi: 10.1371/journal.pone.0254772
[19] Si, S., Tewara, M. A., Ji, X., Wang, Y., Liu, Y., Dai, X. ... Xue, F. (2020). Body surface area, height, and body fat percentage as more sensitive risk factors of cancer and cardiovascular disease. Cancer Medicine, 9(12), 4433-4446. doi: 10.1002/cam4.3076
[20] Tromme, I., Devleesschauwer, B., Beutels, P., Richez, P., Praet, N., Sacré, L. ... Speybroeck, N. (2014). Selective use of sequential digital dermoscopy imaging allows a cost reduction in the melanoma detection process: a Belgian study of patients with a single or a small number of atypical nevi. PLoS One, 9(10), e109339. doi: 10.1371/journal.pone.0109339
[21] Yeh, I. (2020). New and evolving concepts of melanocytic nevi and melanocytomas. Modern Pathology, 33(1), 1-14. doi: 10.1038/s41379-019-0390-x
[22] Zhou, D., Wu, J., & Luo, G. (2016). Body mass index and risk of non-melanoma skin cancer: cumulative evidence from prospective studies. Scientific Reports, 6(1), 1-8. doi: 10.1038/srep37691
How to Cite
Nabil Basim, Y. H. (2021). Features of skinfold thickness in men with benign nevi. Reports of Morphology, 27(4), 59-64. https://doi.org/10.31393/morphology-journal-2021-27(4)-09

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