CT assessment of the height of the coronary arteries orifice location and the height of the aortic sinuses in women with structural changes in the coronary arteries

Keywords: coronary artery orifice, anatomy, computed tomography, aorta, measurements, aortic sinuses.

Abstract

The most common form of cardiovascular disease in Ukraine is coronary heart disease, which is characterized by damage to the coronary arteries. The height of the aortic sinuses and the height of the coronary arteries are assessed when planning interventional procedures and cardiac surgery. Computed tomography can verify structural changes in the coronary arteries and morphometrically evaluate the components of the aortic sac. The purpose of the study: to measure the height of the coronary arteries orifice; height of the aortic sinuses in women with structural changes of the coronary arteries using computed tomography and assess the interdependence of measurements with anthropometric indicators (age, height, weight, body mass index, body surface area). Computed tomography-angiography of the chest of females with coronary arteries were processed. Statistical analysis: Shapiro-Francia test (correctness of distribution), Student’s t-test (comparison of the height of the coronary arteries and the height of the aortic sinuses); Pearson’s linear correlation; Fisher’s multifactorial regression analysis. The study found a direct correlation between height and measurability in women with coronary artery disease. The value of the growth rate was directly correlated with the height of the right aortic sinus (r=0.85, p=0.001), with the height of the lower edge of the right coronary artery orifice (r=0.74, p=0.01), the height of the upper edge of the left coronary artery orifice (r=0.67, p=0.03), the height of the upper edge of the right coronary artery orifice (r=0.67, p=0.03). It is proved that with increasing body surface area, the parameters of the right aortic sinus decrease: the inverse strong correlation r=-0.83, p=0.002. Significant direct relationships have been established between most of the measured components of the aortic root. Multifactor regression analysis showed a proven strong effect of anthropometric data and age on the height of the right aortic sinus: R=0.96, at p=0.009 (according to Fisher). This made it possible to build a model for predicting the height of the right aortic sinus depending on anthropometric and age parameters. Thus, in women with structural lesions of the coronary arteries, the increase in height correlates with an increase in the height of the right aortic sinus, the height of the coronary arteries orifice. An increase in body surface area correlates with a decrease in the height of the right aortic sinus in women with structural lesions of the coronary arteries.

References

Berdajs, D. A. (2016). Aortic root morphology: a paradigm for successful reconstruction. Interactive cardiovascular and thoracic surgery, 22(1), 85-91. doi: 10.1093/icvts/ivv290

Blanke, P., Weir-McCall, J. R., Achenbach, S., Delgado, V., Hausleiter, J., Jilaihawi, H., ... & Leipsic, J. A. (2019). Computed tomography imaging in the context of transcatheter aortic valve implantation (TAVI)/transcatheter aortic valve replacement (TAVR) an expert consensus document of the Society of Cardiovascular Computed Tomography. JACC: Cardiovascular Imaging, 12(1), 1-24. doi: 10.1016/j.jcct.2018.11.008

Forte, E., Punzo, B., Salvatore, M., Maffei, E., Nistri, S., Cavaliere, C., & Cademartiri, F. (2020). Low correlation between biometric parameters, cardiovascular risk factors and aortic dimensions by computed tomography coronary angiography. Medicine, 99(35). doi: 10.1097/MD.0000000000021891

Heitkemper, M., Sivakumar, S., Hatoum, H., Dollery, J., Lilly, S. M., & Dasi, L. P. (2021). Simple 2-dimensional anatomic model to predict the risk of coronary obstruction during transcatheter aortic valve replacement. The Journal of thoracic and cardiovascular surgery, 162(4), 1075-1083. doi: 10.1016/j.jtcvs.2020.01.085

Hennessey, B., Vera-Urquiza, R., Mejía-Rentería, H., Gonzalo, N., & Escaned, J. (2020). Contemporary use of coronary computed tomography angiography in the planning of percutaneous coronary intervention. The International Journal of Cardiovascular Imaging, 36(12), 2441-2459. doi: 10.1007/s10554-020-02052-8

Jinnouchi, H., Sato, Y., Sakamoto, A., Cornelissen, A., Mori, M., Kawakami, R., ... & Finn, A. V. (2020). Calcium deposition within coronary atherosclerotic lesion: Implications for plaque stability. Atherosclerosis, 306, 85-95. doi: 10.1016/j.atherosclerosis.2020.05.017

Merz, A. A., & Cheng, S. (2016). Sex differences in cardiovascular ageing. Heart, 102(11), 825-831. doi: 10.1136/heartjnl-2015-308769

Nasr, A. Y., & El Tahlawi, M. (2018). Anatomical and radiological angiographic study of the coronary ostia in the adult human hearts and their clinical significance. Anatomy & cell biology, 51(3), 164-173. doi: 10.5115/acb.2018.51.3.164

Pidvalna, U. Y., Beshley, D. M., Mirchuk, M. Z., & Mateshuk-Vatseba, L. R. (2021). Normal values of coronary arteries branching height in women. Reports of Morphology, 27(4), 41-46. doi: 10.31393/morphology-journal-2021-27(4)-06

Roth, G. A., Mensah, G. A., Johnson, C. O., Addolorato, G., Ammirati, E., Baddour, L. M., ... & GBD-NHLBI-JACC Global Burden of Cardiovascular Diseases Writing Group. (2020). Global burden of cardiovascular diseases and risk factors, 1990–2019: update from the GBD 2019 study. Journal of the American College of Cardiology, 76(25), 2982-3021. doi: 10.1016/j.jacc.2020.11.010

Silventoinen, K., Zdravkovic, S., Skytthe, A., McCarron, P., Herskind, A. M., Koskenvuo, M., ... & Kaprio, J. (2006). Association between height and coronary heart disease mortality: a prospective study of 35,000 twin pairs. American Journal of Epidemiology, 163(7), 615-621. doi: 10.1093/aje/kwj081

Stolzmann, P., Knight, J., Desbiolles, L., Maier, W., Scheffel, H., Plass, A., ... & Alkadhi, H. (2009). Remodelling of the aortic root in severe tricuspid aortic stenosis: implications for transcatheter aortic valve implantation. European radiology, 19(6), 1316-1323. doi: 10.1007/s00330-009-1302-0

Team, R. C. (2021). R software (software environment for statistical computing and graphics), version 4.0.5. Retrieved from https://www.r-project.org/

Teraura, H., Suzuki, T., & Kotani, K. (2019). Association of taller stature with lower cardiovascular disease mortality in Asian people: a systematic review. Journal of physiological anthropology, 38(1), 1-5. doi: 10.1186/s40101-019-0197-y

Vos, T., Lim, S. S., Abbafati, C., Abbas, K. M., Abbasi, M., Abbasifard, M., ... & Bhutta, Z. A. (2020). Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet, 396(10258), 1204-1222. doi: 10.1016/S0140-6736(20)30925-9

Wang, X., Ren, X. S., An, Y. Q., Hou, Z. H., Yu, Y. T., Lu, B., & Wang, F. (2021). A Specific Assessment of the Normal Anatomy of the Aortic Root in Relation to Age and Gender. International Journal of General Medicine, 14, 2827-2837. doi: 10.2147/IJGM.S312439

World Health Organization. (2017). Cardiovascular diseases. Retrieved from 17 May 2017 website: https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds)

Yeboah, J., Blaha, M. J., Michos, E. D., Qureshi, W., Miedema, M., Flueckiger, P., ... & Bertoni, A. G. (2017). Adult height, prevalent coronary artery calcium score, and incident cardiovascular disease outcomes in a multiethnic cohort. American journal of epidemiology, 186(8), 935-943. doi: 10.1093/aje/kwx165

Published
2022-02-23
How to Cite
Pidvalna, U. Y., Beshley, D. M., & Mateshuk-Vatseba, L. R. (2022). CT assessment of the height of the coronary arteries orifice location and the height of the aortic sinuses in women with structural changes in the coronary arteries. Reports of Morphology, 28(1), 27-33. https://doi.org/10.31393/morphology-journal-2022-28(1)-04