Densitometric assessment in the justification of rehabilitation of patients with atrophy of the bone tissue of the mandible, on the right side

Keywords: mandible, computed tomography, densitometry, bone atrophy.


Densitometric methods for determining bone density are increasingly becoming fundamental in research and a priority in clinical applications in medical practice. Rehabilitation of patients with bone atrophy becomes impossible without assessing its density and, at the same time, is an important component in the diagnosis and planning of reconstructive surgery, in particular, prognosticity in the use of osteoplastic materials or osteointegration of dental implants. The aim of the study was to conduct a densitometric assessment to substantiate the rehabilitation of patients with atrophy of the mandible, on the right side, in the age groups of 25 to 75 years. Computed tomography digital scan scans obtained using the Vatech PaX-I 3D Green extra-oral radiography system and processed by the standardized X-ray diagnostic software Ez3D-I Original ver. Using the tools of the horizontal option panel, in particular the keys of the interface “profile”, the density of bone tissue with interpretation in conventional units of grayness (CUG) in the projection of 4.6, 4.7 teeth was investigated. To obtain qualitatively homogeneous values, we used nonparametric methods of statistical analysis of comparison of age groups – using the multidimensional Kruskal-Wallis test as an alternative intergroup analysis of variance, for simultaneous comparison of three samples. It is proved that during the statistical analysis of bone density using the Mann-Whitney U test in the studied areas of the mandible on the right, the total average number of M experimental (E) groups compared to the average number of the control group (C), high reliability in vertical (VP) measurements and confirmed p<0.05. Thus, it is proved that the early loss of the masticatory group of teeth, in the first group of studies (25-45 years), leads to high rates, with increasing bone density in the direction of distalization of the final defect of the dentition. Conversely, the lack of functional action on bone tissue in the second (46-60 years) and third (61-75 years) groups of the study, leads to a decrease in its density, and, consequently, to the devastation of the trabecular layer, which contributes to the progression of atrophic processes.


Abdelmohsen, A. M. (2017). Comparsion of central and peripheral bone mineral density measurements in postmenopausal women. Journal of Chiropractic Medicine, 16(3), 199-203. doi: 10.1016/j.jcm.2017.08.001

Bouchard, A. L., Dsouza, Ch., Julien, С., Rummler, М., Gaumond, M-H., Cermakian, N., & Willie, B. M. (2022). Bone adaptation to mechanical loading in mice is affected by circadian rhythms. Bone, (154), 116218. doi: 10.1016/j.bone.2021.116218

Evensen, E., Skeie, G., Wilsgaard, T., Christoffersen, T., Dennison, E., Furberg, A.-S., … & Emaus, N. (2018). How is adolescent bone mass and density influenced by early life body size and growth? The Tromsø Study: Fit Futures – A longitudinal cohort study from Norway. JBMR, 2(5), 268-280. doi: 10.1002/jbm4.10049

Farzanegan, F., Zarch, S. H. H., Mobasheri, M. F., & Rangrazi, A. (2019). Evaluation of the Relationship Between Morphology, Volume, and Density of the Mandible and Dentofacial Vertical Dimension Using Cone Beam Computed Tomography. Pesqui. Bras. Odontopediatria Clín. Integr., 19(1), 1-8. doi: 10.4034/PBOCI.2019.191.128

He, J., Xu, S., Zhang, B., Xiao, Ch., Chen, Z., Si, F., … Chen, J. (2020). Gut microbiota and metabolite alterations associated with reduced bone mineral density or bone metabolic indexes in postmenopausal osteoporosis. Aging (Albany NY), 12(9), 8583-8604. doi: 10.18632/aging.103168

Heimes, D., Schiegnitz, E., Kuchen, R., Kämmerer, P. W., & Al-Nawas, B. (2021). Buccal Bone Thickness in Anterior and Posterior Teeth-A Systematic Review. Healthcare (Basel), 9(12), 1-33. doi: 10.3390/healthcare 9121663

Hutchinson, E. F., Farella, M., Hoffman, J., & Kramer, B. (2017). Variation in bone density across the body of the immature human mandible. Journal of Anatomy, 230(5), 679-688. doi: 10.1111/joa.12591

Ihnatiev, O. M., Ermolenko, T. O., Turchyn, M. I., Paniuta, O. I., & Prutiian, T. L. (2020). Маркери метаболізму кісткової тканини: лекції [Markers of bone metabolism: lectures]. Вісник морської медицини – Bulletin of Marine Medicine, 2(87), 127-148. doi: 10.5281/zenodo.3976574

Jankowski, L. G., Warner, S., Gaither, K., Lenchik. L., Fan, B., Lu, Y., & Shepherd, J. J. (2019). Cross-calibration, Least Significant Change and Quality Assurance in Multiple Dual-Energy X-ray Absorptiometry Scanner Environments: 2019 ISCD Official Position. Clin. Densitom., 22(4), 472-483. doi: 10.1016/j.jocd.2019.09.001

Kawata, K., Narita, K., Washio, A., Kitamura, Ch., Nishihara, T., Kubota, S., & Takeda, S. (2021). Odontoblast differentiation is regulated by an interplay between primary cilia and the canonical Wnt pathway. Bone, (150), 116001. doi: 10.1016/j.bone.2021.116001

Khuder, T., Yunus, N., Sulaiman, E., Ibrahim, N., Khalid, T., & Masood, M. (2017). Association between occlusal force distribution in implant overdenture prostheses and residual ridge resorption. Journal of Oral Rehabilitatiom, 44(5), 398-404. doi: 10.1111/joor.12504

Kralick, A. E., & Zemel, B. S. (2020). Evolutionary perspectives on the developing skeleton and implications for lifelong health. Front. Endocrinol, (Lausanne), (11), 1-11. doi: 10.3389/fendo.2020.00099

Kuroiedova, V. D., Vyzhenko, Ye. Ye., Stasiuk, A. A., Halych, L. B., & Petrova, A. V. (2020). Оптична щільність різних відділів щелеп ортодонтичних пацієнтів в період формування зубощелепної системи [Optical density of different parts of jaws in orthodontic patients during dentofacial development]. Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії – Actual Problems of the Modern Medicine: Bulletin of Ukrainian Medical Stomatological Academy, 3(71), 60-64. doi: 10.31718/2077-1096.20.3.60

Lukyanets, E. Yu. (2021). Оцінка мінеральної щільності кісткової тканини та алгоритмів 10-річного ризику остеопоротичних переломів у жінок [Estimation of bone mineral density and algorithms of 10-year risk of osteoporotic fractures in women]. Ліки України – Medicines of Ukraine, 5(251), 31-34. doi: 10.37987/1997-9894.2021.5(251).238139

Maló, P., de Araújo Nobre, M., Lopes, A., Ferro, A., & Botto, J. (2019). The All on 4 treatment concept for the rehabilitation of the completely edentulous mandible: A longitudinal study with 10 to 18 years of follow-up. Clin. Implant. Dent. Relat. Res., 21(4), 565-577. doi: 10.1111/cid.12769

Martínez-Rodríguez, A., Sánchez-Sánchez, J., Vicente-Martínez, M., Martínez-Olcina, M., Miralles-Amorós, L., & Sánchez-Sáez, J. A. (2021). Anthropometric dimensions and bone quality in international male beach handball players: junior vs. senior comparison. Nutrients, 13(6), 1817. doi: 10.3390/nu13061817

Morgan, E. F., Unnikrisnan, G. U., & Hussein, A. I. (2018). Bone mechanical properties in healthy and diseased states. Ann. Rev. Biomed. Eng., (20), 119-143. doi: 10.1146/annurev-bioeng-062117-121139

Morse, L. R., Biering-Soerensen, F., Carbone, L. D., Cervinka, T., Cirnigliaro, C. M., Johnston, T. E., & … Craven, B. C. (2019). bone mineral density testing in spinal cord injury: ISCD official position. J. Clin. Densitom., 22(4), 554-566. doi: 10.1016/j.jocd.2019.07.012

Ohiomoba, H., Sonis, A., Yansane, A., & Friedland, B. (2017). Quantitative evaluation of maxillary alveolar cortical bone thickness and density using computed tomography imaging. American Journal of Orthodontics and Dentofacial Orthopedics, 151(1), 82-91. doi: 10.1016/j.ajodo.2016.05.015

Oshurko, A. P. (2021). Прогресивність вітчизняних та світових наукових обгрунтувань у реабілітації пацієнтів із атрофією кісткової тканини, ускладненої топографо-анатомічною особливістю каналу нижньої щелепи [Progressiveness of domestic and international scientific researches on patient rehabilitation with bone atrophy complicated by the topographical and anatomical peculiarity of the mandibular canal]. Вісник проблем біології і медицини – Bulletin of Problems Biology and Medicine, 162(4), 55-60. doi: 10.29254/2077-4214-2021-4-162-55-60

Oshurko, A. P., Oliinyk, I. Yu., Yaremchuk, N. I., & Makarchuk, I. S. (2021). Morphological features of bone tissue in “disuse atrophy” on the example of a segment of the human lower jaw: clinical experience of treatment. Biomedical and Biosocial Anthropology, (42), 5-11. doi: 10.31393/bba42-2021-01

Owen, R., & Reilly, G. C. (2018). In vitro models of bone remodelling and associated disorders. Front. Bioeng. Biotechnol., (6), 1-22. 00134

Ramanauskaite, A., Becker, K., Kassira, H. C., Becker, J., Sader, R., & Schwarz, F. (2020). The dimensions of the facial alveolar bone at tooth sites with local pathologies: A retrospective cone-beam CT analysis. Clin. Oral. Investig., 24(4), 1551-1560. doi: 10.1007/s00784-019-03057-x

Remmers, S. J. A., de Wildt, B. W. M., Vis, M. A. M., Spaander, E. S. R., de Vries, R. B. M., Ito, K., & Hofmann, S. (2021). Osteoblast-osteoclast co-cultures: A systematic review and map of available literature. National Library of Medicine, 16(11), e0257724. doi: 10.1371/journal.pone.0257724

Rodionova, S. S., & Khakimov, U. R. (2018). Факторы риска дефицита минеральной плотности костной ткани и низкоэнергетического перелома при первичных формах остеопороза у мужчин [Risk factors of bone mineral density deficit and low-energy fractures in primary osteoporosis in men]. Вестник травматологии и ортопедии имени Н.Н. Приорова – Bulletin of traumatology and orthopedics named after N. N. Priorov, (1), 22-29. doi: 10.32414/0869-8678-2018-1-22-29

Rossi, M., Bruno, G., de Stefani, A., Perri, A., & Gracco, A., (2017). Quantitative CBCT evaluation of maxillary and mandibular cortical bone thickness and density variability for orthodontic miniplate placement. International Orthodontics, 15(4), 610-624. doi: 10.1016/j.ortho.2017.09.003

Schafmeyer, L., Linden, T., Sill, H., Rehberg, M., Schoenau, E., & Duran, I. (2022). Pediatric Reference Centiles of Bone Mineral Density and Body Composition of Lower Limbs. Journal of Clinical Densitometry, 25(1), 73-80. doi: 10.1016/j.jocd.2021.07.013

The International Society for Clinical Densitometry (Adult) Official Positions. (2019). 1-35.

Tian, L., Yang, R., Wei, L., Liu, J., Yang, Y., Shao, F. … Guo T. (2017). Prevalence of osteoporosis and related lifestyle and metabolic factors of postmenopausal women and elderly men: A cross-sectional study in Gansu province, Northwestern of China. Medicine (Baltimore), 96(43), e8294. doi: 10.1097/MD.0000000000008294

Tsepkolenko, V. O., Pshenychnyi, T. Y., Holiuk, Ye. L., Tymochuk, V. V., & Derkach, R. V. (2021). Використання аутомезоконцентрату тромбоцитів у пацієнтів з патологією опорно-рухового апарату [The Platelet Automesoconcentrate in Patients with Orthopedical Pathology]. Український журнал медицини, біології та спорту – Ukrainian Journal of Medicine, Biology and Sport, 29(1), 160-167. doi: 10.26693/jmbs06.01.160

Whitney, D. G., Hurvitz, E. A., & Caird, M. S. (2021). Critical periods of bone health across the lifespan for individuals with cerebral palsy: Informing clinical guidelines for fracture prevention and monitoring. Bone, (150), 116009. doi: 10.1016/j.bone.2021.116009

Williams, K. M., Darukhanavala, A., Hicks, R., & Kelly, A. (2022). An Update on Methods for Assessing Bone Quality and Health in Cystic Fibrosis. Journal of Clinical & Translational Endocrinology, (27), 100281. doi: 10.1016/j.jcte.2021.100281

Wismeijer, D., & Chen, S. T. (2018). Proceedings of the Sixth ITI Consensus Conference. Clin. Oral. Impl. Res., 29(Suppl. 16), 5-7. doi: 10.1111/clr.13301

How to Cite
Oshurko, A. P. (2022). Densitometric assessment in the justification of rehabilitation of patients with atrophy of the bone tissue of the mandible, on the right side. Reports of Morphology, 28(1), 42-47.