Micromorphometric changes in rats spleen in the first 7 days after skin burns and under application of infusion solutions


  • Yu.I. Guminskiy
  • I.V. Gunas
  • N.P. Ocheretna
  • O.I. Bashinska
Keywords: micromorphometry, spleen, rats, 0.9% NaCl solution, lactoprotein with sorbitol, НАES-LX-5%

Abstract

In the experiment, during 7 days, were studied changes in the relative volume of white and red spleen pulp of rats without burn and after burning of the skin with 0.9% solution of NaCl, lactoprotein with sorbitol or HAES-LX-5%. When introducing infusion solutions for animals without burning of skin set only 10-13% higher relative volume of white pulp and 7-11% lower values of the relative volume of red pulp when injected lactoprotein with sorbitol than with the introduction of 0.9% NaCl solution or HAES-LX-5%. On the background of skin burns set: reduction when administrating lactoprotein with sorbitol by 4.1%, and when HAES-LX-5% applied by 7.8% of the relative volume of white pulp from 1 to 7 days of the experiment; higher (14.4 and 18.0% respectively) values of the relative volume of white pulp and smaller (7.1 and 9.1% respectively) of the relative volume of red pulp in rats after 3 days after burning of the skin at the administration of HAES-LX-5% or lactoprotein with sorbitol than in animals at a given time when administering 0.9% NaCl solution; larger by 19.4% values of relative volume of white pulp and 5.8% smaller by the value of the relative volume of red pulp in rats 7 days after skin burns when HAES-LX-5% solution is injected than in animals of present the term with administration of 0.9% NaCl solution; less by 7.9% values of the relative amount of red pulp in rats 7 days after skin burns when administering lactoprotein solution with sorbitol than in animals at this time administering with 0.9% NaCl solution.

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Published
2017-10-27
How to Cite
Guminskiy, Y., Gunas, I., Ocheretna, N., & Bashinska, O. (2017). Micromorphometric changes in rats spleen in the first 7 days after skin burns and under application of infusion solutions. Reports of Morphology, 23(2), 240-244. Retrieved from https://morphology-journal.com/index.php/journal/article/view/55
Section
ORIGINAL INVESTIGATIONS